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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECK
All Species:
22.12
Human Site:
Y521
Identified Species:
54.07
UniProt:
O95980
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95980
NP_066934.1
971
106457
Y521
S
G
D
P
C
L
P
Y
F
C
V
Q
G
C
K
Chimpanzee
Pan troglodytes
XP_520575
971
106469
Y521
S
G
D
P
C
L
P
Y
F
C
V
Q
G
C
K
Rhesus Macaque
Macaca mulatta
XP_001083599
971
106512
Y521
S
G
D
P
C
L
P
Y
S
C
V
Q
G
C
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0J1
971
106117
Y521
S
A
D
P
C
L
P
Y
S
C
V
Q
G
C
K
Rat
Rattus norvegicus
NP_001101424
920
100041
S514
V
N
R
K
G
C
P
S
G
D
P
C
L
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521006
935
102603
Y494
P
G
E
L
C
L
P
Y
F
C
V
Q
G
C
K
Chicken
Gallus gallus
XP_418897
963
105683
Y515
S
G
E
L
C
L
P
Y
L
C
V
P
G
C
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648733
1071
117775
Y609
Q
R
G
G
N
Q
G
Y
S
C
I
P
G
C
N
Honey Bee
Apis mellifera
XP_392031
925
102011
L506
Q
G
E
I
C
Q
L
L
H
H
G
R
Q
A
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790172
719
79733
D315
T
R
L
A
K
G
V
D
P
V
G
L
C
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.9
N.A.
N.A.
92.8
86.9
N.A.
85.7
83.8
N.A.
N.A.
N.A.
30.6
33.5
N.A.
34
Protein Similarity:
100
99.9
99.2
N.A.
N.A.
95.7
90.3
N.A.
91.2
90.8
N.A.
N.A.
N.A.
48.8
51.5
N.A.
47.9
P-Site Identity:
100
100
93.3
N.A.
N.A.
86.6
6.6
N.A.
80
73.3
N.A.
N.A.
N.A.
26.6
13.3
N.A.
0
P-Site Similarity:
100
100
93.3
N.A.
N.A.
86.6
6.6
N.A.
86.6
80
N.A.
N.A.
N.A.
33.3
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
70
10
0
0
0
70
0
10
10
70
0
% C
% Asp:
0
0
40
0
0
0
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% F
% Gly:
0
60
10
10
10
10
10
0
10
0
20
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
60
% K
% Leu:
0
0
10
20
0
60
10
10
10
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
10
0
0
40
0
0
70
0
10
0
10
20
0
10
0
% P
% Gln:
20
0
0
0
0
20
0
0
0
0
0
50
10
0
0
% Q
% Arg:
0
20
10
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
50
0
0
0
0
0
0
10
30
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
0
10
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _